Save Big & Start with our NES Scanner Total Wellness Bundle for $279!
Show Me!

Some Foods May Affect Replication of Coronavirus

Some foods may affect replication of coronavirus.


A new study by plant biologists at North Carolina State University in Raleigh has found that chemical compounds in certain foods including muscadine grapes, green tea, cacao powder and dark chocolate can bind to an enzyme, or protease, present in the SARS-CoV-2 virus, and interfere with the virus’s ability to replicate and cause COVID-19 symptoms.[1]

Lamenting the high toll COVID-19 has taken on the world so far, as well as the unknown potential for risks associated with new experimental COVID-19 vaccines, along with lack of viable therapies other than those still in research stages, the NC State researchers set out to evaluate the potential impact of specific nutraceuticals in foods and medicinal plants for preventing or affecting the health outcomes of COVID-19 infections.[2]

Study Focuses on the “Main Protease” of SARS-CoV-2

As described by De-Yu Xie, PhD, professor of plant and microbial biology at NC State and corresponding author of the study, proteases have critical roles to play in the function of cells and viruses. Impeding their normal behaviors has the effect of preventing a number of important functions such as replication.

Focusing on the ability of certain medicinal plants to either prevent a virus from attaching to a human cell or from propagating within the cell, the researchers used both computer simulations and laboratory studies to look at how the “main protease” (Mpro) in the SARS-CoV-2 virus reacted to specific plant compounds already recognized for their anti-inflammatory and antioxidant properties. For SARS-CoV-2, the Mpro protein is an important player in the replication and transcription processes of the virus and so represents a particularly promising target. Xie explained that, “Mpro in SARS-CoV-2 is required for the virus to replicate and assemble itself…If we can inhibit or deactivate this protease, the virus will die.”

Some foods may affect replication of coronavirus.
Some foods may affect replication of coronavirus.
Some foods may affect replication of coronavirus.
Some foods may affect replication of coronavirus.

Muscadine Grapes, Cacao Powder, Green Tea, Dark Chocolate Appear to Inhibit Functionality of Virus

For the computer simulation phase of trial, the researchers used two different types of software (Dock Prep tool of UCSF-Chimera and AutoDock vina), to perform “docking simulations,” a computer simulation technique used to model the potential interaction between two molecules.[3] The computer simulations showed that chemical compounds from two different varieties of muscadine grapes, cacao powder, green tea and dark chocolate all bound to different portions of the Mpro, filling what are essentially “pockets” on the protease and disabling its normal functionality.

In vitro lab studies conducted by doctoral student and first author of the study Yue Zhu confirmed the predicted outcome. All of the test compounds were found to be powerful inhibitors of Mpro function. At 100 μg/ml tested, the extracts from both the green tea and the two muscadine grape cultivers completely inhibited the Mpro activity and the extracts of the cacao and dark chocolate reduced the Mpro activity by 40 to 50 percent.[4]

As Dr. Xie put it, “Plants use these compounds to protect themselves, so it is not surprising that plant leaves and skins contain these beneficial compounds.”[5] They concluded by saying, “although these natural extracts have not been tested for the inhibitory efficacy in animals and humans, based on their inhibitory activity in vitro, we propose that an increased consumption of these common products can enhance preventing SARS-CoV-2 infection and COVID-19 symptoms.”[6]


[1] Xie DY, Kulikowski M. Chemical Compounds in Foods Can Inhibit a Key SARS-CoV-2 Enzyme. North Carolina State University News Nov. 30, 2020.

[2] Zhu Y, Xie DY. Docking Characterization and in vitro Inhibitory Activity of Flavan-3-ols and Dimeric Proanthocyanidins Against the Main Protease Activity of SARS-Cov-2Front Plant Sci Nov. 30, 2020.

[3] Molecular Docking Simulation. ResearchGate 2020.

[4] See Reference [2].

[5] See Reference [1].

[6] See Reference [2].


  • Founder and visionary behind Juneva Health with a personal drive and passion to help clients around the world to better manage and restore optimal health throughout their body in the most natural and supportive way. He takes a personal approach to health care, getting to know clients and connecting on an emotional level to fully understand their individual health situation. Wolfgang strongly believes that people should be in charge of their own health and wants to bring this new 'information (bioenergetic) medicine' system to wider public awareness. He's a NES-certified bioenergetic and homeopathic practitioner who graduated from the Los Angeles School of Homeopathy and holds an engineering and business degree.

Leave a Reply

Your email address will not be published. Required fields are marked *

Juneva Health Your health and wellness is our passion!
Need Help? Have Questions or Feedback? We love to hear from you.
Subscribe To Our Newsletter

Subscribe To Our Newsletter

Join our mailing list to receive the latest news and updates from our team.

You have Successfully Subscribed!

Pin It on Pinterest

Share This

Share this post with your friends!